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Reproduction
Unlocking Longevity: Does Delaying Menopause Hold the Key?
Delaying Menopause: The Secret to Women's Health? We all want to live as long as possible while retaining good health. The problem is this: the older one gets, the higher the risk of age-related diseases. For women, there is a potential increased risk of certain health problems post-menopause. So, could delaying menopause reduce these risks?…
Pets
Rapamycin for Dogs? Randomized Controlled Trial Gives Hope to Middle-Aged Canines
Trials on Rapamycin for Dogs Make Perfect Sense Researchers chose pet dogs for this randomized controlled trial (RCT) for several reasons. They wanted to unlock the secrets of aging by studying our furry friends. But why companion dogs? Pet owners consider dogs as part of the family. After all, they share our lives and many…
Safety
Long-Term Rapamycin Effects on Metabolism in Marmoset Monkey Trials
Long-Term Rapamycin Exposure Tests Closer to Home In this rapamycin (Rapa) study, the experiments lasted for 14 months. It's a significant step forward compared to other research carried out on lab mice. But why monkeys? Primates are closer relatives to humans than rodents, making the results more relevant to us. Also, the small size of…
Aging & Longevity
Rapamycin Treatments in Aged Mice and Non-Human Primates Improves Healthy Aging and Longevity
Beyond Mice: Positive Healthy Aging Results for Primates This 2019 study tested the safety of rapamycin when used as a drug to slow aging effects in marmosets. OK, monkeys are not human. Still, primates are closer relatives to us than mice, which have been the test subjects for most longevity research. If these results hold…
Heart, Kidney, Liver & Lungs
Short-Term Rapamycin Boosts Heart Function in Aged Mice After Stopping Treatment
Heart Benefits from Transient Rapamycin Treatment Imagine a simple drug that could improve your heart's function even after you stop taking it. It sounds like science fiction, but it's not. Rapamycin, or Rapa, is an existing natural drug that has great promise for the future of heart health. This article explores a 2017 study by…
Aging & Longevity
Does Topical Rapamycin Cream Reduce Skin Aging?
Introduction to Rapamycin and Skin Aging For years, rapamycin (Rapa) has been an invaluable anti-rejection drug for organ transplants. A 2019 study now suggests it shows promise for fighting those visible signs of aging. The study tested topical rapamycin's ability to enhance skin appearance and skin health. Early findings suggest it has real potential as…
Aging & Longevity
Short-Term Rapamycin Treatment Boosts Lifespan and Healthspan in Mice
Introduction: Dirt Drug Boosts Lifespan 60% in Mice The FDA approved rapamycin, a special compound found in soil, over 20 years ago. The drug's full potential is still unknown, hence the continual research. In this study, middle-aged mice were treated with Rapa for only 3 months (90 days). The treatment groups were 600 days old,…
Aging & Longevity
Rapamycin Extends Life Span in Genetically Diverse Mice
Study Overview: Rapamycin Extends Life Span The human quest for living longer and staying healthy is as old as the hills. Before scientists can look for solutions, they first need to understand the problem. In this case, that meant knowledge of the aging process. Only then can they develop "potential" treatments that extend lifespan and…
Aging & Longevity
The Dirty Drug and the Ice Cream Tub. Rapamycin Discovery Out!
The Radiolab podcast uses special storytelling techniques to take listeners on fascinating adventures. In this episode, curiosity takes the lead, sparking a craving to know more. Radiolab contributor and narrator Avir Mitra takes us on an amazing journey. It begins with a sample of soil taken from a patch of land in a far-off part…
Aging & Longevity
Rapamycin Longevity Treatment Looks Promising, but Questions Remain
Redefine Aging: Renewed Quest for a Long, Healthy Life Is 70 really the new 50? Many older people think so, refusing to accept the typical state of decline some of their peers encounter in the so-called twilight years. Why do they think they can change the trajectory of those later years when others expect to…