Study Uncovers How Cells React to Starvation A research team at Washington University has found another way that cells deal with stress. Led by Kyusik Kim, the team saw that when a key molecule (eIF4E) gets used up, it sets a unique stress response in motion within the cell. This previously unknown process helps the…

Mega Rapamycin Study Uncovers Clues to Longevity This research revised 29 studies on rapamycin (Rapa) from varied sources. Researchers wanted to see if there was enough evidence from multiple studies to support Rapa's longevity claims. The results showed that the drug helped mice live longer in trials, especially females. One of the interesting findings was…

Treating Gum Disease with an Anti-Aging Drug! Scientists at the University of Washington and The Jackson Laboratory tested rapamycin on aging mice. The purpose of this experiment was to see if Rapa was a possible solution for treating gum disease. Researchers were also keen to explore oral health more generally and its impact on well-being.…

Junk Food, Obesity, and Longer Life! In the fight against aging, a new study on mice by researchers in Buffalo, NY, showed promising results. This experiment on mice revealed some interesting outcomes. Researchers injected the animals weekly with the drug rapamycin (Rapa). They fed the test subjects fattening foods to get them into an obese…

How Food Influences Healthspan and Aging There is a lot of cell research going on in pursuit of understanding and improving healthspan and aging. In this study, the focus is on the protein called mTOR, which acts like a boss giving orders inside your cells. One of its functions is to keep a close check…

Translational Geroscience: A New Model for Medicine Prepare for a shift from the traditional disease-specific approach by medics to one that's more focused on aging. Scientists believe that the old way of treating age-related diseases one by one is ending. The time has come to move away from sick care to healthcare. This is where…

Meet the Speakers The Aging Science Podcast is hosted by Kamil Pabis, aka The Aging Scientist. Pabis has the ability to explain complex scientific concepts to a broader audience. In this episode, he interviews Professor Adam Salman, a leading expert in aging research. Salman talks about the things that have the most influence on how…

What Is mTOR—Exactly? mTOR is a molecule or protein (building block) inside your body. It controls functions such as cell growth, energy, cell survival, and the creation of new proteins. There is huge interest in mTOR within scientific aging circles. This is because of its role in healthspan and longevity. With a better understanding of…

Promising Drug, Phase 2 Trial, New Hope for FAP Biodexa Pharmaceuticals PLC is a clinical-stage biologic (biopharmaceutical) drug company. It's known for developing the kind of medicines that help people suffering from otherwise hard-to-treat conditions. The article looks at a Phase 2 trial using eRapa to treat Familial Adenomatous Polyposis (FAP). This genetic condition causes…

Study: Rapamycin (Rapa) Effects on Ovarian Lifespan Nanjing Medical University and Heilongjiang Bayi Agricultural University led this fascinating study. Researchers explored the short-term effects of rapamycin treatment on ovarian lifespan in mice. The China-based trial wanted to see if a 2-week Rapa regime could extend ovarian function. Most importantly, could this happen without harmful long-term…